MTHFR C677T and A1298C: Explained In Plain English

[Last updated 5th October, 2021] All humans have certain genetic variations or “mutations” that can influence our health. One of the more well-studied variations is known as an MTHFR mutation; more specifically MTHFR C677T and A1298C. Unfortunately, not only is the concept of genetics difficult, but the terminology makes it even more confusing. This article attempts to clarify what an MTHFR C677T and A1298C mutation is, in a way you can understand. ContentsWhat is MTHFR?What is MTHFR C677T and MTHFR A1298C?What Is Heterozygous and Homozygous MTHFR?List of Common MTHFR Mutation VariationsMTHFR C677T and A1298C and HomocysteineWhich MTHFR Mutation Is A Problem? What is MTHFR? MTHFR is a critical enzyme in the body. It’s required for a metabolic process that repairs DNA, switches genes on and off, and numerous other important functions (1). MTHFR is also essential to convert folate and folic acid – each a form of … Continue reading MTHFR C677T and A1298C: Explained In Plain English