MTHFR C677T and A1298C: Explained In Plain English
All humans have certain genetic variations or “mutations” that can influence our health. One of the more well-studied variations is known as an MTHFR mutation; more specifically MTHFR C677T and A1298C. Unfortunately, not only is the concept of genetics difficult, but the terminology makes it even more confusing. This article attempts to clarify what an MTHFR C677T and A1298C mutation is, in a way you can understand. What is MTHFR? MTHFR is a critical enzyme in the body. It’s required for a metabolic process that repairs DNA, switches genes on and off, and numerous other important functions (1). MTHFR is also essential to convert folate and folic acid – each a form of Vitamin B9 – into the biologically active form called L-methylfolate (or 5-MTHF). Not to be confused with the enzyme, the MTHFR gene provides the instructions for making that MTHFR enzyme. In other words, it “triggers” production of … Continue reading MTHFR C677T and A1298C: Explained In Plain English
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